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        Nc2Eye

           A curated ncRNAomics knowledgebase for bridging basic and clinical research in eye diseases.

Detail of diabetic retinopathy (DR)
ncRNA name Nek7 siRNA
ncRNA Category siRNA
Disease name diabetic retinopathy (DR)
Species Homo sapiens
Tissues/Cell_line human retinal endothelial cells (HRECs)
Methods siRNA transfection, CCK-8 assay, Western blot, Co-immunoprecipitation assay, qPCR, ELISA, immunofluorescence, TUNEL assay
Expression pattern associated
Functional description Depletion of NEK7 inhibited NLRP3 inflammasome activation induced by high glucose in HRECs.
PubMed ID 28726778
Year 2017
Title Protection of Mcc950 against high-glucose-induced human retinal endothelial cell dysfunction.
Drug-related ncRNA NO

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