ncRNA name | Nek7 siRNA |
ncRNA Category | siRNA |
Disease name | diabetic retinopathy (DR) |
Species | Homo sapiens |
Tissues/Cell_line | human retinal endothelial cells (HRECs) |
Methods | siRNA transfection, CCK-8 assay, Western blot, Co-immunoprecipitation assay, qPCR, ELISA, immunofluorescence, TUNEL assay |
Expression pattern | associated |
Functional description | Depletion of NEK7 inhibited NLRP3 inflammasome activation induced by high glucose in HRECs. |
PubMed ID | 28726778 |
Year | 2017 |
Title | Protection of Mcc950 against high-glucose-induced human retinal endothelial cell dysfunction. |
Drug-related ncRNA | NO |
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